| Identification | Back Directory | [Name]
MOLGRASTIM | [CAS]
99283-10-0 | [Synonyms]
HGM-CSF
RHGM-CSF
MOLGRASTIM
HUMAN CSF-2
HUMAN GM-CSF
GM-CSF, HUMAN
Molgramostime
HUMAN MGI-1GM
Molgramostimum
Unii-B321al142j
Molgramostim CRS
REC GM-CSF (HUMAN)
RECOMBINANT HUMAN GM-CSF
HUMAN PLURIPOIETIN-ALPHA
Molgramostime [inn-french]
Molgramostimum [inn-latin]
rHuGM-CSF, Recombinant Human GM-CSF
GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR
HUMAN GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR
COLONY STIMULATING FACTOR-GRANULOCYTE/MACROPHAGE HUMAN
GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR, HUMAN
REC GRANULOCYTE-MACROPHAGE-COLONY STIMULATING FACTOR (HUMAN)
GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR, HUMAN, RECOMBINANT
GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR, HUMAN, RECOMBINANT, E COLI | [MDL Number]
MFCD07785399 |
| Chemical Properties | Back Directory | [Appearance]
Clear, colourless liquid. | [storage temp. ]
-15°C | [form ]
lyophilized powder | [color ]
white to off-white | [biological source]
human | [Water Solubility ]
water: soluble 0.010mL, clear, colorless |
| Hazard Information | Back Directory | [Chemical Properties]
Clear, colourless liquid. | [Uses]
Antineutropenic; hematopoietic stimulant. | [General Description]
Package size based on protein content | [Biochem/physiol Actions]
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth and differentiation factor for cells in the granulocyte, macrophage and eosinophil lineage. GM-CSF stimulates colony formation from pluripotential progenitor cells at extremely low concentrations and is an essential survival and proliferative factor for hematopoietic progenitor cells in all divisions up to maturity. It also stimulates growth in some epithelial cells and osteoclasts. GM-CSF is produced by a variety of cell types (monocytes, endothelial cells, T-cells, fibroblasts, mitogen-stimulated B-cells, and LPS-stimulated macrophages). GM-CSF is secreted as a single chain glycoprotein containing 128 amino acids for human with a conserved disulfide bond. Human and murine GM-CSF share approx. 54% sequence homology and do not cross-react in bioactivity. |
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