| Identification | Back Directory | [Name]
BMS-791325 | [CAS]
958002-36-3 | [Synonyms]
BMS-791325
BMS 791325-08
BMS-791325 1G
BMS-791325 HCl
Beclabuvir HCl
PubChem ID: 72722244
Beclabuvir hydrochloride
BMS 791325 hydrochloride
BMS-791325 Beclabuvir hydrochloride | [Molecular Formula]
C36H46ClN5O5S | [MOL File]
958002-36-3.mol | [Molecular Weight]
696.3 |
| Hazard Information | Back Directory | [Enzyme inhibitor]
This potent allosteric inhibitor (FW = 673.87 g/mol) targets hepatitis C virus NS5B polymerase IC50 <0.5 nM (biochemical assay) and EC50 = 0.8-6 nM (replicon assay). Unlike prior cyclopropyl-fused indolobenzazepine inhibitors, BMS-791325 has improved solubility and membrane permeability properties as well as reduced off-target activities, directed most notably against human pregnane X receptor (hPXR) transactivation. |
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| Company Name: |
Wuhan Topule
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| Tel: |
+86-02787215551 +86-19945035818 |
| Website: |
http://www.topule.com/ |
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