| Identification | Back Directory | [Name]
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile | [CAS]
950596-58-4 | [Synonyms]
Erlotinib Hydrochloride iMpurity 23
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile
Benzonitrile, 2-amino-4,5-bis(2-methoxyethoxy)-
2-((4-chloro-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol | [EINECS(EC#)]
1308068-626-2 | [Molecular Formula]
C13H18N2O4 | [MDL Number]
MFCD16619377 | [MOL File]
950596-58-4.mol | [Molecular Weight]
266.29 |
| Chemical Properties | Back Directory | [Melting point ]
73-77 °C | [Boiling point ]
445.5±45.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
1.85±0.10(Predicted) | [color ]
Pale Beige to Beige |
| Hazard Information | Back Directory | [Uses]
2-((4-Chloro-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol is an impurity if Erlotinib (E625008) a EGFR-targeted drug in the treatment of non-small cell lung cancer. | [Uses]
2-Amino-4,5-bis(2-methoxyethoxy)benzonitrile is an impurity of Erlotinib (E625008), a EGFR-targeted drug in the treatment of non-small cell lung cancer. EGFR small tyrosine kinase inhibitor that shows most substantial effect on tumor growth inhibition and animal survival. |
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