Identification | Back Directory | [Name]
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE | [CAS]
947381-58-0 | [Synonyms]
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE 5,8,11,13-Eicosatetraenoic acid, 15-hydroxy-, (1R)-2-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-1-[[(1-oxooctadecyl)oxy]methyl]ethyl ester, (5Z,8Z,11Z,13E,15S)- | [Molecular Formula]
C43H78NO9P | [MOL File]
947381-58-0.mol | [Molecular Weight]
784.07 |
Chemical Properties | Back Directory | [Boiling point ]
805.8±75.0 °C(Predicted) | [density ]
1.037±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml | [pka]
1.17±0.50(Predicted) |
Hazard Information | Back Directory | [Description]
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; ) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes. |
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