| Identification | Back Directory | [Name]
R-afatinib | [CAS]
945553-91-3 | [Synonyms]
Afatinib-2
Afatinib Enantiomer
afatinib impurities139
AFATINIB CHIRAL IMPURITY
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-
(R,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetra-
hydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)
but-2-enamide
(R,E)-N-(4-((3-Chloro-4- fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinozolin- 6-yl)-4-(dimethylamino)but-2-enamide
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
(R,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide? (Afatinib Impurity）
Afatinib impurity 3/R-afatinib/(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide | [Molecular Formula]
C24H25ClFN5O3 | [MOL File]
945553-91-3.mol | [Molecular Weight]
485.94 |
| Hazard Information | Back Directory | [Uses]
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide, is an impurity of Afatinib (A355300) an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. |
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