Identification | Back Directory | [Name]
SUC-LEU-TYR-AMC | [CAS]
94367-20-1 | [Synonyms]
SUC-LY-AMC SUC-LEU-TYR-AMC CALPAIN SUBSTRATE I SUCCINYL-LEU-TYR-AMC SUC-LEU-TYR-AMC USP/EP/BP CALPAIN SUBSTRATE II, FLUOROGENIC SUC-LEU-TYR-7-AMINO-4-METHYLCOUMARIN N-SUCCINYL-LEU-TYR 4-METHYLCOUMARYL-7-AMIDE N-SUCCINYL-LEU-TYR 7-AMIDO-4-METHYLCOUMARIN succinyl-leucyl-tyrosyl-4-methyl-7-coumarylamide Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem L-Tyrosinamide, N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | [Molecular Formula]
C29H33N3O8 | [MDL Number]
MFCD00057900 | [MOL File]
94367-20-1.mol | [Molecular Weight]
551.59 |
Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml | [form ]
Off-white solid | [color ]
off-white |
Hazard Information | Back Directory | [Uses]
Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain that is used to measure the peptidase activity of the 20S proteasome. | [Definition]
ChEBI: Coumarin carrying a methyl group at C-4 and a succinyl-leucyl-tryrosyl side-chain at C-7. | [Biological Activity]
Cell permeable: no''Primary Target Calpain -1 and -2''Product does not compete with ATP.''Reversible: no |
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