| Identification | Back Directory | [Name]
4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride | [CAS]
942518-29-8 | [Synonyms]
H-Dab(N3).HCl
H-L-Aha-OH*HCl
L-Dab(N3)-OH·HCl
H-L-Aha-OH hydrochloride
L-Azidohomoalanine (AHA)
L-Azidohomoalanine hydrochloride
4-Azido-L-homoalanine hydrochloride
(S)-2-Amino-4-azido-butanoic acid HCl
(2S)-2-Amino-4-azido-butanoic acid HCl
(S)-2-Amino-4-azidobutanoic acid hydrochloride
Nγ-Azido-L-2,4-diaminobutyric acid hydrochloride
(2S)-2-Amino-4-azidobutanoic acid hydrochloride (1:1)
Butanoic acid, 2-amino-4-azido-, hydrochloride , (2S)-
Nγ-Azido-L-2,4-diaminobutyric acid hydrochloride≥ 99% (Titration)
4-Azido-L-homoalanine, (S)-2-Amino-4-azidobutanoic acid hydrochloride | [Molecular Formula]
C4H9ClN4O2 | [MDL Number]
MFCD13184931 | [MOL File]
942518-29-8.mol | [Molecular Weight]
180.59 |
| Chemical Properties | Back Directory | [Melting point ]
139°C | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO | [form ]
powder or crystals | [color ]
White to off-white | [Water Solubility ]
Soluble to 100 mM in water |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder | [Uses]
L-Azidohomoalanine (AHA) is an amino acid analog of methionine that contains a very small modification, specifically an azido moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click ” reaction between an azide and an alkyne or cyclooctyne. For example the azido-modified protein can be detected with either fluorescent alkyne or biotin alkyne. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis. | [reaction suitability]
reaction type: click chemistry | [storage]
Store at -20°C |
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