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ChemicalBook--->CAS DataBase List--->938186-76-6

938186-76-6

938186-76-6 Structure

938186-76-6 Structure
IdentificationBack Directory
[Name]

5-OCTADIYNYL-DU CEP
[CAS]

938186-76-6
[Synonyms]

5-OCTADIYNYL-DU CEP
5-Octadiynyl-dU CE-phosphoramidite
5-(OCTA-1,7-DIYNYL)-5-O-DMTr-2-DEOXY URIDINE-3-O-CE-AMIDITE
5'-Dimethoxytrityl-5-(octa-1,7-diynyl)-2'-deoxyuridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-(1,7-octadiyn-1-yl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
[Molecular Formula]

C47H55N4O8P
[MDL Number]

MFCD10687025
[MOL File]

938186-76-6.mol
[Molecular Weight]

834.945
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
[pka]

8.32±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

This functional phosphoramidite is used to introduce click handles univerally (5′ internal and 3′end) into oligonucleotides under standard conditions for solid phase synthesis. Afterwards the oligonucleotide (RNA, PNA, DNA) can be efficiently conjugated using a copper-catalyzed click reaction to azide-functionalized moieties such as fluorescent dye azides and azido amino acids
[reaction suitability]

reaction type: click chemistry
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