| Identification | Back Directory | [Name]
[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl- | [CAS]
934387-35-6 | [Synonyms]
ROCK-IN-1
[1,1'-Biphenyl]-3-carboxamide, 6-(1-aminoethyl)-4'-fluoro-N-4-pyridinyl- | [Molecular Formula]
C20H18FN3O | [MDL Number]
MFCD31544439 | [MOL File]
934387-35-6.mol | [Molecular Weight]
335.37 |
| Hazard Information | Back Directory | [Uses]
ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2. | [IC 50]
ROCK2: 1.2 nM (IC50) | [References]
[1] Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6. DOI:10.1016/j.bmcl.2013.09.040 |
|
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|