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ChemicalBook--->CAS DataBase List--->925448-93-7

925448-93-7

925448-93-7 Structure

925448-93-7 Structure
IdentificationBack Directory
[Name]

SAM-531
[CAS]

925448-93-7
[Synonyms]

SAM-531
WAY-262
PF05212365
PF-05212365
WAY-262,531
P -05212365
Cerlapirdine
N,N-Dimethyl-3-[[3-(1-naphthalenylsulfonyl)-1H-indazol-5-yl]oxy]-1-propanamine
1-Propanamine, N,N-dimethyl-3-[[3-(1-naphthalenylsulfonyl)-1H-indazol-5-yl]oxy]-
antagonist,inhibit,5-HT Receptor,5-hydroxytryptamine,5-HT6,oral,Cerlapirdine,PF 05212365,selective,Alzheimer's disease,Serotonin Receptor,5-hydroxytryptamine Receptor,Inhibitor
[Molecular Formula]

C22H23N3O3S
[MDL Number]

MFCD18782738
[MOL File]

925448-93-7.mol
[Molecular Weight]

409.5
Chemical PropertiesBack Directory
[Boiling point ]

662.9±45.0 °C(Predicted)
[density ]

1.300±0.06 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO : 41.67 mg/mL (101.76 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C)
[form ]

Solid
[pka]

9.70±0.40(Predicted)
[color ]

Off-white to yellow
Hazard InformationBack Directory
[Uses]

Cerlapirdine is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor (1). Used in the symptomatic treatment of Alzheimer’s disease.
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