| Chemical Properties | Back Directory | [Boiling point ]
295.6±15.0 °C(Predicted) | [density ]
1.11±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
H2O: 5 mg/mL | [form ]
solid | [pka]
9.41±0.40(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
RJR 2429 is a potent AChR agonist. | [Biological Activity]
Potent nAChR agonist that displays selectivity for α 4 β 2 (K i = 1 nM) and α 1 β γ δ subtypes (EC 50 values are 297 and 55 nM respectively). Induces dopamine release from striatal neurons (EC 50 = 2 nM) and inhibits ion flux in thalamic neurons (IC 50 = 154 nM). Also putative α 3 β 4 agonist that potentiates catecholamine release. |
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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