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ChemicalBook--->CAS DataBase List--->912569-84-7

912569-84-7

912569-84-7 Structure

912569-84-7 Structure
IdentificationBack Directory
[Name]

N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
[CAS]

912569-84-7
[Synonyms]

S-methyl DM1
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (>90%)
[Molecular Formula]

C36H50ClN3O10S
[MDL Number]

MFCD34469122
[MOL File]

912569-84-7.mol
[Molecular Weight]

752.32
Chemical PropertiesBack Directory
[Melting point ]

>152°C (dec.)
[Boiling point ]

936.9±65.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

9.82±0.70(Predicted)
[color ]

Off-White to Pale Yellow
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

N2''-Deacetyl-N2''-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.
[IC 50]

Maytansinoids
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