Identification | Back Directory | [Name]
PHYTOHEMAGGLUTININ PHA-M | [CAS]
9008-97-3 | [Synonyms]
PHA-C PHA-M PHA-P PHA-L Phytolectin PHA-P PHA-L fitohemaglutynina phytohemagglutinin phytohemaglutinins PHA-L AGAROSE BOUND phytohaemagglutinin PHYTOHEMAGGLUTININ-L PHYTOHEMAGGLUTININ-M RED KIDNEY BEAN LECTIN LEUCOAGGLUTININ (PHA-L) Agglutinin from soybean Phytohemagglutinin ,PHA PHYTOHEMAGGLUTININ PHA-M PhytohemagglutininM=PHAM PHA (phytohemagglutinins) PHASEOLUS VULGARIS LECTIN Phytohemagglutinin-M (PHA) pigeonpeaphytohemagglutinin Lectin from Arachis Hypogaea PHASEOLUS VULGARIS AGGLUTININ Phytohaemagglutinin ELISA Kit PHYTOHAEMAGGLUTININSFROMLEGUMES PHYTOHEMAGGLUTIN-LEUKOAGGLUTININ Phytohem- agglutinins and Lectins PHASEOLUS VULGARIS LEUCOAGGLUTININ PHYTOHEMAGGLUTININ PHA-M USP/EP/BP PHASEOLUS VULGARIS AGGLUTININ PHA-L PHA (Phytohemagglutinins), 50-100 ug/ml PHYTOHEMAGGLUTININ-M, PHASEOLUS VULGARIS LECTIN FROM PHASEOLUS VULGARIS & Agglutiniinsand LectinsphytoheMagglutinins Phytohemagglutinins agglutinins and Lectins Agglutinins and Lectins, phytohemagglutinins PHASEOLUS VULGARIS LEUCOAGGLUTININ AGAROSE BOUND lectin from phaseolus vulgaris*phytohemagglutinin LECTIN FROM PHASEOLUS VULGARIS CELL*CULT URE TESTED LECTIN FROM PHASEOLUS VULGARIS*LEUCOAGGL UTININ PHA- Phytohemagglutinin
Phaseolus vulgaris agglutinin, PHA Agglutinin from soybean, PHA-C, Wheat germ agglutinin | [EINECS(EC#)]
232-718-7 | [MDL Number]
MFCD00165279 |
Hazard Information | Back Directory | [Uses]
Phytohemagglutinin-M (PHA-M) has been used in the activation of Jurkat and primary cells. It has also been used to treat polymorphonuclear blood cells(PMBCs) | [General Description]
Lectins are distinct proteins or glycoproteins that have at least one non-catalytic domain which fixes reversibly to a definite mono- or oligosaccharide. Some of their potentially utilizable biological assets include: antitumor, immunomodulatory and anti-insect, antifungal, antibacterial, anti-HIV, and mitogenic properties. | [Biochem/physiol Actions]
Phytohemagglutinin (PHA) has mitogenic and potent cell agglutinating activities. It binds to T-cell membranes and stimulates cell division and metabolic activity. PHA has the ability to stimulate close contacts between cell membranes. | [Enzyme inhibitor]
This class of toxic plant lectins (MW depends on species; CAS 9008-97-3)
is a carbohydrate-binding protein, consisting mainly of the leukoagglutinins
PHA-L and PHA-E, indicating their ability to agglutinate leukocytes and
erythrocytes. Phytohemagglutinins occur at the highest concentrations in
uncooked red and white kidney beans, green beans, broad beans, and fava
beans. Phaseolus vulgaris phytohemagglutinin consists of seven different
glycosylated polypeptides. Phytohemagglutinins induce mitosis, alter
membrane transport, and increase membrane permeability to proteins. In
humans, poisoning can be induced from as few as five raw beans, with
symptoms occurring within three hours, beginning with nausea, then
vomiting, followed by diarrhea. Medical intervention is rarely required. |
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