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ChemicalBook--->CAS DataBase List--->900185-01-5

900185-01-5

900185-01-5 Structure

900185-01-5 Structure
IdentificationBack Directory
[Name]

PIK-293
[CAS]

900185-01-5
[Synonyms]

CS-539
PIK-293
PIK-293 PIK293
PIK-293 USP/EP/BP
PIK-293 (IC-87114)
PIK-293;PIK293;PIK 293
2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one
2-[(4-aminopyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one
2-[(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
4(3H)-Quinazolinone, 2-[(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-
[Molecular Formula]

C22H19N7O
[MDL Number]

MFCD20272930
[MOL File]

900185-01-5.mol
[Molecular Weight]

397.43
Chemical PropertiesBack Directory
[density ]

1.43
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO > 10 mM
[form ]

Powder
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

PIK-293 is a cell-permeable, selective inhibitor of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit p110δ (IC50s = 100, 25, 10, and 0.24 μM for p110 subunit isoforms α, β, γ, and δ, respectively).
[Uses]

PIK-293 is a phosphoinositide 3-kinase delta (PI3Kδ) inhibitor and the parent compound of PIK-294 (P437705). Inhibition of PI3K’s shows to be a promising approach for cancer therapy.
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