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ChemicalBook--->CAS DataBase List--->894783-71-2

894783-71-2

894783-71-2 Structure

894783-71-2 Structure
IdentificationBack Directory
[Name]

BIBF 1202
[CAS]

894783-71-2
[Synonyms]

CS-1313
BIBF 1202
Nintedanib-1
Nintedanib-010
Intedanib Impurity A
Nintedanib impurity A
Nintedanib impuritiesA
Nintedanib impurities26
NintedanibImpurity6-13C-d3
Nintedanib Carboxylic Acid
(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid
(3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, (3Z)-
Nintedanib impurity 9/Nintedanib Carboxylic Acid/(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl) methylene)-2-oxoindoline-6-carboxylic acid
Nintedanib Impurity 6Q: What is Nintedanib Impurity 6 Q: What is the CAS Number of Nintedanib Impurity 6 Q: What is the storage condition of Nintedanib Impurity 6 Q: What are the applications of Nintedanib Impurity 6
[Molecular Formula]

C30H31N5O4
[MDL Number]

MFCD28167767
[MOL File]

894783-71-2.mol
[Molecular Weight]

525.6
Chemical PropertiesBack Directory
[Melting point ]

>216°C (dec.)
[Boiling point ]

759.5±60.0 °C(Predicted)
[density ]

1.331±0.06 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

Aqueous Base (Slightly, Heated)
[form ]

Solid
[pka]

3.94±0.20(Predicted)
[color ]

Light Yellow to Yellow
Hazard InformationBack Directory
[Description]

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
[Uses]

Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.
[storage]

Store at -20°C
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