Identification | Back Directory | [Name]
ANP 1-28, HUMAN | [CAS]
89213-87-6 | [Synonyms]
HANF α-hANP Carperitide ANP 1-28, HUMAN ANF 1-28, HUMAN ANP HUMAN, 1-28 ahANF, Carperitide ANP, ALPHA-, HUMAN Carperitide Acetate α-Atriopeptin【human】 Carperitide impurity ALPHA-ANF (1-28), HUMAN ANP 1-28, HUMAN USP/EP/BP ANF (1-28), HUMAN, PORCINE SLRRSSCFGGRMDRIGAQSGLGCNSFRY [MET(O)12]-ANP (HUMAN, 1-28) Carperitide(ANP(1-28)/human) ALPHA-ANP [1-28] HUMAN, CANINE Atrial natriuretic factor【human】 ATRIAL NATRIURETIC PEPTIDE HUMAN Carperitide Acetate, carperitida Carperitide / Carperitide Acetate atrial natriuretic factor (99-126) Atrial natriuretic peptide【porcine】 ATRIAL NATRIURETIC FACTOR 1-28, HUMAN ATRIAL NATRIURETIC PEPTIDE HUMAN, 1-28 ATRIAL NATRIURETIC PEPTIDE 1-28, HUMAN ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN ATRIAL NATRIURETIC PEPTIDE, ALPHA-, HUMAN Atrial natriureticpeptide-28 (huMan) (9CI) ANP (HUMAN, 1-28) (PORCINE, BOVINE, CANINE) ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, CANINE) ATRIAL NATRIURETIC FACTOR (1-28) (HUMAN, PORCINE) ATRIAL NATRIURETIC PEPTIDE (1-28), HUMAN, PORCINE ALPHA-ATRIAL NATRIURETIC PEPTIDE, HUMAN, RECOMBINANT SLRRSSCFGGRMDRIGAQSGLGCNSFRY (DISULFIDE BRIDGE: 7-23) Atrial Natriuretic Factor (1-28) (huMan)
αhANF, Carperitide [MET(O)12]-A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) Atrial Natriuretic Factor (1-28) (human), αhANF, Carperitide Atrial Natriuretic Peptide (1-28) (human) (trifluoroacetate salt) A-TYPE (ATRIAL) NATRIURETIC PEPTIDE (HUMAN, 1-28) (PORCINE, BOVINE, CANINE) SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET(O)-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH H-SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH (DISULFIDE BRIDGE: 7-23) SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET: O-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR[SLRRSSCFGGR-MET: O-DRIGAQSGLGCNSFRY]DISULFIDE BRIDGE CYS7-CYS23. Atrial Natriuretic Factor (1-28) (human) hydrochloride salt H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH hydrochloride salt (Disulfide bond) L-Tyrosine, L-seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-, cyclic (7→23)-disulfi... | [EINECS(EC#)]
686-482-9 | [Molecular Formula]
C127H203N45O39S3 | [MDL Number]
MFCD00076226 | [MOL File]
89213-87-6.mol | [Molecular Weight]
3080.44 |
Chemical Properties | Back Directory | [density ]
1.55±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Water: 1 mg/ml | [form ]
A lyophilized powder | [Sequence]
H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH,(Disulfide bridge: Cys-Cys) | [InChIKey]
NSQLIUXCMFBZME-VUEHYBQXNA-N |
Hazard Information | Back Directory | [Description]
Carperitide is the α-human atrial natriuretic peptide (α-hANP) produced by
recombinant technology. It was introduced in Japan as a treatment for acute
congestive heart failure (CHF). In dogs with CHF, carperitide significantly reduced the
elevated left ventricular end-diastolic pressure and the index of myocardial oxygen
consumption (systolic blood pressure x heart rate). In a clinical trial, carperitide was
effective in improving hemodynamics and symptoms in 60% of patients with acute CHF.
Carperitide was reported to be well tolerated with no significant adverse effects
clinically. A beneficial effect on hemodynamics has been reported in chronic heart
failure patients. Carperitide is also in clinical trials for maintenance of blood pressure
during surgical operations. | [Originator]
Suntory (Japan) | [Uses]
Treatment of decompensated congestive heart
failure. | [Definition]
ChEBI: Carperitide is a polypeptide. | [Brand name]
Daiichi Suntory, Japan. |
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