| Identification | Back Directory | [Name]
Isogambogenic acid | [CAS]
887923-47-9 | [Synonyms]
Isogambogenic acid
(2E)-4-[(1R,3aS,5S,12aS)-9-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-3a,4,5,7-tetrahydro-8,10-dihydroxy-3,3-dimethyl-11-(3-methyl-2-buten-1-yl)-7,13-dioxo-1,5-methano-1H,3H-furo[3,4-d]xanthen-1-yl]-2-methyl-2-butenoic acid | [Molecular Formula]
C38H46O8 | [MOL File]
887923-47-9.mol | [Molecular Weight]
630.78 |
| Chemical Properties | Back Directory | [Boiling point ]
818.6±65.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
4.72±0.19(Predicted) |
| Hazard Information | Back Directory | [Description]
Isogambogenic acid inhibits angiogenesis and may be a viable drug candidate in anti-angiogenesis therapy.
Isogambogenic acid exhibits an anticancer effect by inducing autophagy-dependent cell death in NSCLC cells, which may be an effective chemotherapeutic agent that can be used against NSCLC in a clinical setting. | [target]
Bcl-2/Bax | Caspase | mTOR | VEGFR | Akt | MAPK |
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