| Identification | Back Directory | [Name]
ETHYL 2,5-DIFLUOROBENZOYLACETATE | [CAS]
887267-53-0 | [Synonyms]
Ethyl 3-(2,5-difluorophenyl)
ETHYL 2,5-DIFLUOROBENZOYLACETATE
ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%
Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester
3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester
2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester | [Molecular Formula]
C11H10F2O3 | [MDL Number]
MFCD07783808 | [MOL File]
887267-53-0.mol | [Molecular Weight]
228.19 |
| Hazard Information | Back Directory | [Uses]
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate is commonly utilized in organic synthesis as C-nucleophiles. One specific example is its reaction with the N-terminal electrophile CF3CHN2, resulting in the formation of CF3-heterocycles, namely ethyl 6-fluoro-4-oxo-1-(2,2,2-trifluoroethyl)-1,4-dihydrocinnoline-3-carboxylate[1].
 | [References]
[1] Arkhipov A, et al. Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2):
Electrophilicity of the Terminal N?Atom. Organic Letters, 2016; 18: 3406–3409. |
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