| Identification | Back Directory | [Name]
Manassantin B | [CAS]
88497-88-5 | [Synonyms]
Manassantin B
Saucernetin 7
Saucernetin B
1,3-Benzodioxole-5-methanol, α-[(1R)-1-[4-[(2S,3R,4R,5S)-5-[4-[(1R,2R)-2-(3,4-dimethoxyphenyl)-2-hydroxy-1-methylethoxy]-3-methoxyphenyl]tetrahydro-3,4-dimethyl-2-furanyl]-2-methoxyphenoxy]ethyl]-, (αR)- | [Molecular Formula]
C41H48O11 | [MDL Number]
MFCD32068060 | [MOL File]
88497-88-5.mol | [Molecular Weight]
716.81 |
| Chemical Properties | Back Directory | [Melting point ]
83-86℃ | [Boiling point ]
831.1±65.0 °C(Predicted) | [density ]
1.219±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
2-8°C | [form ]
Solid | [pka]
13.35±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Manassantin B (compound 6) is a kind of lignan. Manassantin B can be isolated from the ethyl acetate extract of the roots of Saururus chinensis. Manassantin B has cytotoxicities against HT-29 with an IC50 value of 12 μM[1]. | [References]
[1] Yeun-Kyung Lee, et al. Inhibition of DNA topoisomerases I and II and cytotoxicity by lignans from Saururus chinensis. Archives of Pharmacal Research. 2009, 32. |
|
|