| Identification | Back Directory | [Name]
Naxagolide | [CAS]
88058-88-2 | [Synonyms]
L-64739
CS-1515
(+)-PHNO
Naxagolide
Naxagolida
Naxagolidum
Naxagolide [inn]
(+)-PHNO88058-88-2
Naxagolide free base
Naxagolide/Dopazinol
Naxagolidum [inn-latin]
Naxagolida [inn-spanish]
4-Propyl-9-hydroxynaphoxazine
(+)-4-Propyl-9-hydroxynaphoxazine
4-Propyl-9-hydroxy-1,2,3,4a,5,6-hexahydronaphthoxazine
(4aR)-3,4,4aβ,5,6,10bα-Hexahydro-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-9-ol
(4aR,10bR)-3,4,4a,5,6,10b-Hexahydro-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-9-ol
2H-Naphth[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-, (4aR,10bR)-
2H-Naphth(1,2-B)-1,4-oxazin-9-ol, 3,4,4A,5,6,10B-hexahydro-4-propyl-, (4ar-trans)-
NAXAGOLIDE [INN]; PHNO; NAXAGOLIDUM [INN-LATIN]; NAXAGOLIDA [INN-SPANISH]; 88058-88-2 | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C15H21NO2 | [MDL Number]
MFCD00866577 | [MOL File]
88058-88-2.mol | [Molecular Weight]
247.336 |
| Hazard Information | Back Directory | [Uses]
Antiparkinsonian;dopamine agonist. | [Definition]
ChEBI: Naxagolide is an organic heterotricyclic compound that is (4aR,10bR)-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazine substituted by propyl and hydroxy groups at positions 4 and 9, respectively. It is a potent dopamine D2-receptor agonist and its hydrochloride salt was under clinical development by Merck & Co as a potential antiparkinsonian agent (now discontinued). It has a role as an antiparkinson drug, a dopamine agonist and an anticonvulsant. It is a tertiary amino compound, an organic heterotricyclic compound and a member of phenols. It is a conjugate base of a naxagolide(1+). | [storage]
Store at -20°C |
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