| Identification | Back Directory | [Name]
FMOC-TYR(TBU)-SER(PSI-ME,MEPRO)-OH | [CAS]
878797-09-2 | [Synonyms]
Fmoc-Tyr(tBu)-Ser[Ψ(Me,Me)Pro]-OH
FMOC-TYR(TBU)-SER(PSI-ME,MEPRO)-OH
Fmoc-L-Tyr(tBu)-L-Ser[PSI(Me,Me)Pro]-OH
FMOC-TYR(TBU)-SER(ΨME,ME PRO)-OH_878797-09-2
Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH≥ 99% (HPLC)
(9H-Fluoren-9-yl)MethOxy]Carbonyl Tyr(tBu)-SerPsi(Me, Me)Pro-OH
(4S)-3-(FMOC-TYR(TBU))-2,2-DIMETHYL-OXAZOLIDINE-4-CARBOXYLIC ACID
(S)-3-[Nα-(9-Fluorenylmethyloxycarbonyl)-O-tert-butyl-L-tyrosinyl]-2,2-dimethyloxazolidine-4-carboxylic acid
(4S)-3-[(2S)-3-[4-(tert-butoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid
(4S)-3-[(2S)-3-[4-(1,1-Dimethylethoxy)phenyl]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]-2,2-dimethyl-4-oxazolidinecarboxylic acid
4-Oxazolidinecarboxylic acid, 3-[(2S)-3-[4-(1,1-dimethylethoxy)phenyl]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]-2,2-dimethyl-, (4S)- | [Molecular Formula]
C34H38N2O7 | [MDL Number]
MFCD02682872 | [MOL File]
878797-09-2.mol | [Molecular Weight]
586.67 |
| Chemical Properties | Back Directory | [Boiling point ]
795.6±60.0 °C(Predicted) | [density ]
1.238±0.06 g/cm3(Predicted) | [storage temp. ]
Store at +2°C to +8°C. | [form ]
powder | [pka]
3.09±0.40(Predicted) | [InChIKey]
DNJYPUYQFPFOKS-VMPREFPWSA-N | [SMILES]
O1C[C@@H](C(O)=O)N(C(=O)[C@@H](NC(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)CC2=CC=C(OC(C)(C)C)C=C2)C1(C)C |
| Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Uses]
Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH is mainly used in peptide synthesis. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-damaging proline-like TFA-labile oxazolidine. The reason for introducing the pseudoproline residue as a dipeptide is that it avoids the acylation of the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in a single step. The serine residue is regenerated in the normal trans fatty acid mediated cleavage reaction. | [reaction suitability]
reaction type: Fmoc solid-phase peptide synthesis |
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