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IdentificationBack Directory
[Synonyms]

m-PEG5-Boc
mPEG5-t-buyl ester
mPEG5-CH2CH2COOtBu
m-PEG5-t-butyl ester
tert-butyl 2,5,8,11,14-pentaoxaheptadecan-17-oate
4,7,10,13,16-Pentaoxaheptadecanoic acid, 1,1-dimethylethyl ester
Chemical PropertiesBack Directory
[solubility ]

Soluble in DMSO, DMF, DCM
Hazard InformationBack Directory
[Description]

m-PEG5-t-buyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses]

m-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] Balasingam Radhakrishnan, et al. Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof. US20060018874A1.
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