| Identification | Back Directory | [Name]
MEDICA 16 | [CAS]
87272-20-6 | [Synonyms]
MEDICA 16
3,3,14,14-TETRAMETHYLHEXADECANEDIOIC ACID
3,3,14,14-TETRAMETHYLHEXADECANEDIONIC ACID
Hexadecanedioic acid, 3,3,14,14-tetramethyl- | [Molecular Formula]
C20H38O4 | [MDL Number]
MFCD00797684 | [MOL File]
87272-20-6.mol | [Molecular Weight]
342.51 |
| Chemical Properties | Back Directory | [Melting point ]
154-159 °C
| [Boiling point ]
485.9±18.0 °C(Predicted) | [density ]
0.984±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO: 28 mg/mL
| [form ]
solid
| [pka]
4.51±0.10(Predicted) | [color ]
white
|
| Hazard Information | Back Directory | [Description]
MEDICA 16 is a β,β''-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol. | [Uses]
MEDICA 16 is a β,β'-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol. | [Definition]
ChEBI: MEDICA 16 is an alpha,omega-dicarboxylic acid that is hexadecanedioic acid carrying methyl groups at positions 3 and 14. It is a free fatty acid 1 (FFA1/GPR40) receptor agonist and an ATP citrate lyase inhibitor, and exhibits hypolipidemic and antidiabetogenic properties. It has a role as an antilipemic drug, an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor, an EC 2.3.3.8 (ATP citrate synthase) inhibitor, a G-protein-coupled receptor agonist and a hypoglycemic agent. | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
|