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ChemicalBook--->CAS DataBase List--->872514-65-3

872514-65-3

872514-65-3 Structure

872514-65-3 Structure
IdentificationBack Directory
[Name]

Rilotumumab
[CAS]

872514-65-3
[Synonyms]

Rilotumumab
Rilotumumab (anti-HGF)
Research Grade Rilotumumab(DHD03702)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Rilotumumab is an anti-HGF antibody that prevents ligand binding to MET and its activation.
[Clinical Use]

A phase I/II trial of rilotumumab in combination with erlotinib was evaluated in previously treated NSCLC patients with metastatic disease. The results indicated a favorable safety profile and success in terms of disease control rate. A phase Ib/II trial of rilotumumab or ganitumab in combination with etoposide and carboplatin or cisplatin was evaluated in extensive-stage SCLC patients.
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