| Identification | Back Directory | [Name]
N-[2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)phenoxy]ethyl]-N-methylglycinehydrochloride | [CAS]
868265-28-5 | [Synonyms]
LY2365109
LY 2365109;LY-2365109
LY 2365109 hydrochloride
N-[2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)phenoxy]ethyl]-N-methylglycinehydrochloride | [Molecular Formula]
C22H27NO5 | [MOL File]
868265-28-5.mol | [Molecular Weight]
385.45 |
| Chemical Properties | Back Directory | [Boiling point ]
556.2±50.0 °C(Predicted) | [density ]
1.187±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
Soluble to 100 mM in DMSO and to 50 mM in ethanol | [form ]
Powder | [pka]
2.27±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
LY 2365109 Hydrochloride is a potent and selective glycine transporter 1 (GlyT1) inhibitor. | [in vivo]
LY2365109 (0.3-30 mg/kg; p.o.) produces dose-dependent elevations of Sprague–Dawley rats in CSF levels of glycine[1].
| [storage]
Desiccate at RT |
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