| Identification | Back Directory | [Name]
2-(Benzyloxyethoxyethoxy)ethylaMine | [CAS]
86770-75-4 | [Synonyms]
CAS_86770-75-4
Benzyl-PEG3-NH2
H2N-(CH2CH2O)3-Bn
Benzyl-PEG3-amine
BnO-PEG2-CH2CH2NH2
2-[2-(2-Benzyloxy-ethoxy)-ethoxy
2-(Benzyloxyethoxyethoxy)ethylaMine
2-(2-(2-(benzyloxy)ethoxy)ethoxy)ethanamine | [Molecular Formula]
C13H21NO3 | [MDL Number]
MFCD22383750 | [MOL File]
86770-75-4.mol | [Molecular Weight]
239.31 |
| Hazard Information | Back Directory | [Biological Activity]
Benzyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
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