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ChemicalBook--->CAS DataBase List--->863975-32-0

863975-32-0

863975-32-0 Structure

863975-32-0 Structure
IdentificationBack Directory
[Name]

BZ-NLE-LYS-ARG-ARG-AMC
[CAS]

863975-32-0
[Synonyms]

Bz-nLKRR-AMC
Bz-Nle-KRR-AMC
BZ-NLE-LYS-ARG-ARG-AMC
Bz-Nle-KRR-AMC (hydrochloride)
Bz-Nle-Lys-Arg-Arg-AMC trifluoroacetate salt
BZ-NLKRR-AMC;BZ-NLE-LYS-ARG-ARG-AMC;863975-32-0
L-Argininamide, N-benzoyl-L-norleucyl-L-lysyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
[Molecular Formula]

C41H60N12O7
[MDL Number]

MFCD18782523
[MOL File]

863975-32-0.mol
[Molecular Weight]

832.99
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
[form ]

A solid
Hazard InformationBack Directory
[Description]

Bz-Nle-KRR-AMC is a fluorogenic peptide substrate for yellow fever virus (YFV) non-structural 3 (NS3) and dengue virus (DV) NS2B/3 serine proteases. Upon enzymatic cleavage by YFV NS3 or DV NS2B/3 serine proteases, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify YFV NS3 or DV NS2B/3 serine protease activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
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