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ChemicalBook--->CAS DataBase List--->852433-84-2

852433-84-2

852433-84-2 Structure

852433-84-2 Structure
IdentificationBack Directory
[Name]

Dovitinib Dilactic acid (TKI258 Dilactic acid)
[CAS]

852433-84-2
[Synonyms]

CS-208
TKI258 Dilactic acid
CHIR-258 DILACTIC ACID
Dovitinib dilactic acid
Dovitinib dilactic acid, >=99%
Dovitinib Dilactic Acid (TKI258
Dovitinib (TKI-258) Dilactic Acid
Dovitinib Dilactic acid (TKI258 Dilactic acid)
Dovitinib Dilactic acid (TKI258 Dilactic acid) USP/EP/BP
2-Hydroxypropanoic acid compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
[Molecular Formula]

C24H27FN6O4
[MDL Number]

MFCD22420807
[MOL File]

852433-84-2.mol
[Molecular Weight]

482.52
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO > 10 mM
[form ]

Powder
Hazard InformationBack Directory
[Uses]

Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively.
[Uses]

Dovitinib Dilactic acid is the Dilactic acid of Dovitinib (D537000, Lactate salt), which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit), also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Potent FGFR inhibitor
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