Identification | Back Directory | [Name]
Dovitinib Dilactic acid (TKI258 Dilactic acid) | [CAS]
852433-84-2 | [Synonyms]
CS-208 TKI258 Dilactic acid CHIR-258 DILACTIC ACID Dovitinib dilactic acid Dovitinib dilactic acid, >=99% Dovitinib Dilactic Acid (TKI258 Dovitinib (TKI-258) Dilactic Acid Dovitinib Dilactic acid (TKI258 Dilactic acid) Dovitinib Dilactic acid (TKI258 Dilactic acid) USP/EP/BP 2-Hydroxypropanoic acid compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone | [Molecular Formula]
C24H27FN6O4 | [MDL Number]
MFCD22420807 | [MOL File]
852433-84-2.mol | [Molecular Weight]
482.52 |
Hazard Information | Back Directory | [Uses]
Dovitinib (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively. | [Uses]
Dovitinib Dilactic acid is the Dilactic acid of Dovitinib (D537000, Lactate salt), which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit), also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Potent FGFR inhibitor |
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