| Identification | Back Directory | [Name]
KR-32568 | [CAS]
852146-73-7 | [Synonyms]
KR 32568,KR32568
KR-32568 >=98% (HPLC), solid
2-Furancarboxamide, N-(aminoiminomethyl)-5-(5-fluoro-2-methylphenyl)- | [Molecular Formula]
C13H12FN3O2 | [MDL Number]
MFCD08705324 | [MOL File]
852146-73-7.mol | [Molecular Weight]
261.25 |
| Chemical Properties | Back Directory | [Melting point ]
176 °C | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ~10 mg/mL | [form ]
solid | [pka]
7.31±0.46(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Biological Activity]
Sodium/hydrogen exchanger-1 (NHE-1) inhibitor; IC50 = 0.23 μM; inhibited NHE-1-mediated rabbit platelet swelling; in anesthetized ratsreduced infarct size from 67% (control) to 43% ( at 0.1 mg/kg) and 24% ( at 1.0 mg/kg); reduced number of ventricular premature beats from 530 to 266 ( at 0.1 mg/kg) and 115 ( at 1.0 mg/kg); reduced ventricular fibrillation incidence from 17 to 8 (0.1 mg/kg) and 0 (1.0 mg/kg); implications for research and treatment of myocardial ischemic diseases. | [storage]
Store at -20°C |
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BOC Sciences
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DC Chemicals
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Energy Chemical
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