| Identification | Back Directory | [Name]
ARP 101 | [CAS]
849773-63-3 | [Synonyms]
Butanamide, 2-[([1,1'-biphenyl]-4-ylsulfonyl)(1-methylethoxy)amino]-N-hydroxy-3-methyl-, (2R)- | [Molecular Formula]
C20H26N2O5S | [MDL Number]
MFCD09753277 | [MOL File]
849773-63-3.mol | [Molecular Weight]
406.5 |
| Hazard Information | Back Directory | [Definition]
ChEBI: N(2)-([biphenyl]-4-ylsulfonyl)-N-hydroxy-N(2)-isopropoxy-D-valinamide is a hydroxamic acid that is N-hydroxy-D-valinamide in which the alpha-amino group has been substituted by isopropoxy and [biphenyl]-4-ylsulfonyl groups. A selective matrix metalloproteinase-2 (MMP-2) inhibitor, it is one of the most potent inducers of autophagy. Its physiological roles include angiogenesis, cancer metastasis, embryogenesis, tissue remodeling in development, and wound healing. It has a role as an EC 3.4.24.24 (gelatinase A) inhibitor, an autophagy inducer, an antineoplastic agent and a melanin synthesis inhibitor. It is a hydroxamic acid and a D-valine derivative. | [storage]
Desiccate at 4°C |
|
|