| Identification | Back Directory | [Name]
2-Cyano-4-fluoropyridine | [CAS]
847225-56-3 | [Synonyms]
4-Fluoropicolinonitrile
2-Cyano-4-fluoropyridine
4-fluoropyridine-2-carbonitrile
4-Fluoro-2-pyridinecarbonitrile
2-Pyridinecarbonitrile, 4-fluoro-
2-Cyano-4-fluoropyridine ISO 9001：2015 REACH
2-Cyano-4-fluoropyridine, 4-Fluoropicolinonitrile | [Molecular Formula]
C6H3FN2 | [MDL Number]
MFCD09834127 | [MOL File]
847225-56-3.mol | [Molecular Weight]
122.1 |
| Chemical Properties | Back Directory | [Melting point ]
72-74℃ | [Boiling point ]
221℃ | [density ]
1.24 | [Fp ]
88℃ | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [form ]
powder | [pka]
-1.44±0.10(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Application]
The 2-cyano-4-fluoropyridine is a novel fluorine-containing medical intermediate and has wide application in the field of medicine. | [Preparation]
(1)4-chloropyridine-2-formamide is prepared by taking 4-chloropyridine-2-methyl formate and ammonia water as raw materials through an ammonolysis reaction;
(2) dehydrating 4-chloropyridine-2-formamide under the action of a dehydrating agent to obtain 2-cyano-4-chloropyridine;
(3) 2-cyano-4-chloropyridine is subjected to halogen exchange reaction to obtain 2-cyano-4-fluoropyridine.
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