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ChemicalBook--->CAS DataBase List--->84709-25-1

84709-25-1

84709-25-1 Structure

84709-25-1 Structure
IdentificationBack Directory
[Name]

d-Epigalbacin
[CAS]

84709-25-1
[Synonyms]

epigalbacin
(-)-Zuonin A
d-Epigalbacin
1,3-Benzodioxole, 5,5'-[(2S,3R,4S,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl]bis-
[Molecular Formula]

C20H20O5
[MOL File]

84709-25-1.mol
[Molecular Weight]

340.37
Chemical PropertiesBack Directory
[Boiling point ]

460.6±45.0 °C(Predicted)
[density ]

1.258±0.06 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[form ]

Solid
[color ]

White to off-white
Spectrum DetailBack Directory
[Spectrum Detail]

d-Epigalbacin(84709-25-1)1HNMR
Hazard InformationBack Directory
[Biological Activity]

(-)-Zuonin A (D-Epigalbacin), a natural lignin, is a potent and selective inhibitor of JNKs with IC50 values of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively.
[in vitro]

(?)-zuonin A binds the D-recruitment site (DRS) of JNK, a recruitment site utilized by substrates and other substrates to dock onto and recognize MAPKs.
(?)-zuonin A

[target]

JNK1

1.7 μM (IC 50 )

JNK2

2.9 μM (IC 50 )

JNK3

1.74 μM (IC 50 )

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