Identification | Back Directory | [Name]
d-Epigalbacin | [CAS]
84709-25-1 | [Synonyms]
epigalbacin (-)-Zuonin A d-Epigalbacin 1,3-Benzodioxole, 5,5'-[(2S,3R,4S,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl]bis- | [Molecular Formula]
C20H20O5 | [MOL File]
84709-25-1.mol | [Molecular Weight]
340.37 |
Chemical Properties | Back Directory | [Boiling point ]
460.6±45.0 °C(Predicted) | [density ]
1.258±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [form ]
Solid | [color ]
White to off-white |
Hazard Information | Back Directory | [Biological Activity]
(-)-Zuonin A (D-Epigalbacin), a natural lignin, is a potent and selective inhibitor of JNKs with IC50 values of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively. | [in vitro]
(?)-zuonin A binds the D-recruitment site (DRS) of JNK, a recruitment site utilized by substrates and other substrates to dock onto and recognize MAPKs. (?)-zuonin A | [target]
JNK1 1.7 μM (IC 50 ) | JNK2 2.9 μM (IC 50 ) | JNK3 1.74 μM (IC 50 ) | |
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Company Name: |
cjbscvictory
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Tel: |
13348960310 13348960310 |
Website: |
https://www.weikeqi-biotech.com/ |
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