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ChemicalBook--->CAS DataBase List--->84477-87-2

84477-87-2

84477-87-2 Structure

84477-87-2 Structure
IdentificationBack Directory
[Name]

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
[CAS]

84477-87-2
[Synonyms]

H-7
H-72HCl
1-(5-Isoquinolylsulfonyl)-2-methylpiperazine
1-(5-isoquinolinesulfonyl)-2-methylpiperazine
Isoquinoline-5-sulfonic 2-methyl-1-piperazide
5-(2-methylpiperazine-1-sulfonyl)isoquinoline
1-(5-isoquinolinylsulfonyl)-2-methyl-piperazin
5-(2-methylpiperazin-1-yl)sulfonylisoquinoline
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
5-[(2-methyl-1-piperazinyl)sulfonyl]Isoquinoline
1-(5-isoquinolinylsulfonyl)-2-*methylpiperazine F
Isoquinoline, 5-[(2-methyl-1-piperazinyl)sulfonyl]-
(Isoquinoline-5-yl)(2-methylpiperazine-1-yl) sulfone
1-(5-ISOQUINOLINYLSULFONYL)-2-*METHYLPIP ERAZINE FRE
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Isoquinoline-5-sulfonic 2-methyl-1-piperazide
[Molecular Formula]

C14H17N3O2S
[MDL Number]

MFCD00063403
[MOL File]

84477-87-2.mol
[Molecular Weight]

291.37
Chemical PropertiesBack Directory
[Boiling point ]

495.3±55.0 °C(Predicted)
[density ]

1.277±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

ethanol: 20 mg/mL
[form ]

Solid
[pka]

7.69±0.40(Predicted)
[color ]

White to light yellow
[BRN ]

5482740
Safety DataBack Directory
[WGK Germany ]

3
[RTECS ]

TL9305000
[F ]

10
[Toxicity]

LD50 intravenous in mouse: 94mg/kg
Hazard InformationBack Directory
[Definition]

ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
[Biological Activity]

Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.
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