Identification | Back Directory | [Name]
1-(4-(benzo[d]thiazol-2-yloxy)benzyl)piperidine-4-carboxylic acid | [CAS]
841202-16-2 | [Synonyms]
JNJ-26993135 JNJ-26993135
(JNJ26993135) 1-(4-(benzo[d]thiazol-2-yloxy)benzyl)piperidine-4-carboxylic acid 4-Piperidinecarboxylic acid, 1-[[4-(2-benzothiazolyloxy)phenyl]methyl]- | [Molecular Formula]
C20H20N2O3S | [MOL File]
841202-16-2.mol | [Molecular Weight]
368.45 |
Hazard Information | Back Directory | [Uses]
JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC50 value of 11 nM[1]. | [References]
[1] Marcos Lorca, et al. Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics. Journal of the Serbian Chemical Society 2023 Volume 88, Issue 1, Pages: 25-39. |
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