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ChemicalBook--->CAS DataBase List--->841202-16-2

841202-16-2

841202-16-2 Structure

841202-16-2 Structure
IdentificationBack Directory
[Name]

1-(4-(benzo[d]thiazol-2-yloxy)benzyl)piperidine-4-carboxylic acid
[CAS]

841202-16-2
[Synonyms]

JNJ-26993135
JNJ-26993135 (JNJ26993135)
1-(4-(benzo[d]thiazol-2-yloxy)benzyl)piperidine-4-carboxylic acid
4-Piperidinecarboxylic acid, 1-[[4-(2-benzothiazolyloxy)phenyl]methyl]-
[Molecular Formula]

C20H20N2O3S
[MOL File]

841202-16-2.mol
[Molecular Weight]

368.45
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

JNJ-26993135 is a selective leukotriene A4 hydrolase (LTA4H) inhibitor with the IC50 value of 11 nM[1].
[References]

[1] Marcos Lorca, et al. Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics. Journal of the Serbian Chemical Society 2023 Volume 88, Issue 1, Pages: 25-39.
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