| Identification | Back Directory | [Name]
2-(AMINOMETHYL)-18-CROWN-6 | [CAS]
83585-61-9 | [Synonyms]
2-(AMINOMETHYL)-18-CROWN-6
2-AMinoMethyl-18-crown-6 95%
1,4,7,10,13,16-hexaoxacyclooctadecane-2-methanamine | [Molecular Formula]
C13H27NO6 | [MDL Number]
MFCD00191741 | [MOL File]
83585-61-9.mol | [Molecular Weight]
293.36 |
| Chemical Properties | Back Directory | [Boiling point ]
135 °C/0.08 mmHg (lit.) | [density ]
1.126 g/mL at 25 °C (lit.) | [refractive index ]
n20/D 1.479(lit.) | [Fp ]
113 °C | [form ]
liquid | [pka]
9.11±0.29(Predicted) | [BRN ]
4184588 |
| Hazard Information | Back Directory | [Uses]
2-Aminomethyl-18-crown-6 (AM-18-C-6) can be used to prepare:
- AM-18-C-6 bonded Merrifield peptide resin, which is used to study the absorption and the isotopic effect of magnesium.
- Schiff base of gossypol with aminomethyl crown ether for complexation of monovalent cations.
- Crown tagged triarylphosphine by reacting with triphenylphosphine carboxylic acid. These tagged triarylphosphine reagents are used in Mitsunobu and Heck reactions for the removal of phosphine derived by-products.
- 1,16-hexadecanoyl-bis-(2-aminomethyl)-18-crown-6 (bola A-16), which is utilized as a vesicular carrier in a drug delivery system.
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