| Identification | Back Directory | [Name]
EUQUININE | [CAS]
83-75-0 | [Synonyms]
Euquinin
Euchinine
EUQUININE
tastless quinine
QUININE CARBONIC ETHER
ethyl quinine carbonate
QUININE ETHYL CARBONATE
(8α,9R)-6'-Methoxycinchonan-9-ol ethoxyformate
Quinine, ethyl carbonate (ester) (6CI, 7CI, 8CI)
(8α,9R)-6'-Methoxy-9-(ethoxycarbonyloxy)cinchonan
Carbonic acid ethyl=[(8α,9R)-6'-methoxycinchonan-9-yl] ester
Cinchonan-9-ol, 6'-methoxy-, ethyl carbonate (ester), (8a,9R)- (9CI)
carbonic acid ethyl [(R)-(6-methoxy-4-quinolyl)-[(2S,4R,5R)-5-vinylquinuclidin-2-yl]methyl] ester
[(R)-[(4R,5R,7S)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methyl] ethyl carbonate | [EINECS(EC#)]
201-500-3 | [Molecular Formula]
C23H28N2O4 | [MDL Number]
MFCD00198093 | [MOL File]
83-75-0.mol | [Molecular Weight]
396.48 |
| Chemical Properties | Back Directory | [Melting point ]
94-95 °C | [Boiling point ]
526.3±50.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 79 mg/mL (199.25 mM);Ethanol: 79 mg/mL (199.25 mM) | [pka]
8.84±0.70(Predicted) | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Uses]
Euquinine is an odorless salt that can be used as
a substitute for quinine. Euquinine has anti-Plasmodium falciparum activity.
Euquinine can be used for the study of multidrug resistance and bioavailability
of Plasmodium falciparum [1]. | [storage]
Store at -20°C | [References]
[1] Jamaludin A, et al. Relative bioavailability of the hydrochloride, sulphate and ethyl carbonate salts of quinine. Br J Clin Pharmacol. 1988 Feb;25(2):261-3. DOI:10.1111/j.1365-2125.1988.tb03299.x |
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