| Identification | Back Directory | [Name]
C-(1H-INDOL-5-YL)-METHYLAMINE | [CAS]
81881-74-5 | [Synonyms]
INDOLE-5-METHYLAMINE
Indole-5-methanamine
5-(AMINOMETHYL)INDOLE
5-(aminomethyl)-indol
1H-Indole-5-MethanaMine
((Indol-5-yl)Methyl)aMine
(1H-Indol-5-yl)methylamine
(1H-INDOL-5-YL)METHANAMINE
1-(1H-Indol-5-yl)MethanaMine
C-(1H-INDOL-5-YL)-METHYLAMINE | [Molecular Formula]
C9H10N2 | [MDL Number]
MFCD01719220 | [MOL File]
81881-74-5.mol | [Molecular Weight]
146.19 |
| Chemical Properties | Back Directory | [Melting point ]
114-118 °C
| [Boiling point ]
335.6±17.0 °C(Predicted) | [density ]
1.199±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
solid | [pka]
17.07±0.30(Predicted) |
| Hazard Information | Back Directory | [Uses]
5-(Aminomethyl)indole is used in the synthesis of Vigabatrin (V253000) bioisosteres as inhibitors of γ-aminobutyric acid aminotransferase (GABA-AT) inhibitors. | [Uses]
Reactant for preparation of:• ;HIV-1 integrase inhibitors targeting the catalytic domain and its ability for interaction with LEDGF/p751• ;Inhibitors of Gli1-mediated transcription in the Hedgehog pathway2• ;SCIO-469-like compounds for the inhibition of p38 MAP kinase3• ;4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles as protein kinase c theta (PKC θ) inhibitors4• ;Non-covalent thrombin inhibitors5 |
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