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ChemicalBook--->CAS DataBase List--->79916-77-1

79916-77-1

79916-77-1 Structure

79916-77-1 Structure
IdentificationBack Directory
[Name]

FORSYTHOSIDE A
[CAS]

79916-77-1
[Synonyms]

Forsythiaside
FORSYTHOSIDE A
Forsythiaside A
b-D-Glucopyranoside,2-(3,4-dihydroxyphenyl)ethyl 6-O-(6-deoxy-a-L-Mannopyranosyl)-,4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
2-(3,4-Dihydroxyphenyl)ethyl 6-O-(6-deoxy-α-L-mannopyranosyl)-4-O-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]carbonyl-β-D-glucopyranoside
[Molecular Formula]

C29H36O15
[MDL Number]

MFCD08460220
[MOL File]

79916-77-1.mol
[Molecular Weight]

624.59
Chemical PropertiesBack Directory
[Melting point ]

>127°C (subl.)
[Boiling point ]

911.9±65.0 °C(Predicted)
[density ]

1.60±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

9.31±0.10(Predicted)
[color ]

Off-White to Light Beige
[CAS DataBase Reference]

79916-77-1
Safety DataBack Directory
[HS Code ]

29389090
Questions And AnswerBack Directory
[Overview]

Forsythiaside A is the phenylethanol glycoside component isolated from Forsythia. It has pharmacological effects such as antibacterial, antiviral, antioxidant, anti-infective and antipyretic. It is mainly used for content determination, identification, and pharmacological experiment and so on. Forsythiaside A
[Chemical Properties]

This product appears as white crystalline powder. It is easily soluble in water, ethanol and methanol, but insoluble in ether and chloroform.
[Pharmacological effects]

Forsythoside A has not only antibacterial, anti-infective and antipyretic effects, but also good anti-virus and antioxidant effects.
[Preparation]

Extract 40 g of crushed forsythia leaves with 1200 mL 55% ethanol (volume fraction) at 74 ° C for 50 min, filter and extract twice. The filtrate was combined and concentrated under reduced pressure at 50 °C to recycle the ethanol, obtaining 665 mL of concentrated solution. 35 mL of absolute ethanol was added to give a forsythia leaf extract containing 5% ethanol (volume fraction). The forsythia leaf extract was adsorbed on a 2.6 cm x 25 cm AB-8 resin column and eluted with 50% ethanol to obtain a forsythia leaf extract. The extract of forsythia leaf was extracted for three times with water-saturated n-butanol. Recycle the n-butanol, and dry to obtain crude product. The crude product was separated in 8 cm x 50 cm C18 reverse phase silica gel column chromatography through elution with 30% methanol. Collect the eluent and obtain the pure compound of forsythoside A under reduced pressure.
[Application]

It can be used for content determination, identification and pharmacological experiments.
Hazard InformationBack Directory
[Uses]

Forsythoside A is used as an antiinflammatory agent in traditional Chinese medicine.
[Definition]

ChEBI: Forsythiaside is a hydroxycinnamic acid.
[Biological Activity]

extracted from forsythia suspense (thunb.) vahl dried fruit;store the product in sealed, cool and dry condition
Spectrum DetailBack Directory
[Spectrum Detail]

FORSYTHOSIDE A(79916-77-1)1HNMR
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