| Identification | Back Directory | [Name]
A-3 HYDROCHLORIDE | [CAS]
78957-85-4 | [Synonyms]
A-3
A-3 HYDROCHLORIDE
TRISIALYLATED, GALACTOSYLATED, TRIANTENNARY
N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL
N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE
N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE | [Molecular Formula]
C12H14Cl2N2O2S | [MDL Number]
MFCD00077311 | [MOL File]
78957-85-4.mol | [Molecular Weight]
321.22 |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
173-176°C | [storage temp. ]
−20°C
| [solubility ]
DMSO: 24 mg/mL
| [form ]
solid
| [color ]
white
|
| Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
Inhibits cAMP and cGMP dependent protein kinases. Also inhibits MLC kinase and protein kinase C | [Biochem/physiol Actions]
Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM). |
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