| Identification | Back Directory | [Name]
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide | [CAS]
781652-57-1 | [Synonyms]
CDPPB
mGluR5 Ligand, CDPPB
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
mGluR5 Ligand, CDPPB - CAS 781652-57-1 - Calbiochem
Benzamide, 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)- | [Molecular Formula]
C23H16N4O | [MDL Number]
MFCD12828752 | [MOL File]
781652-57-1.mol | [Molecular Weight]
364.4 |
| Hazard Information | Back Directory | [Uses]
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
| [Biochem/physiol Actions]
CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator. | [storage]
Store at -20°C |
|
| Company Name: |
|
| Tel: |
821-50328103-801 18930552037 |
| Website: |
http://m.is0513.com/ShowSupplierProductsList13285/0.htm |
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|