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ChemicalBook--->CAS DataBase List--->781628-99-7

781628-99-7

781628-99-7 Structure

781628-99-7 Structure
IdentificationBack Directory
[Name]

Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-
[CAS]

781628-99-7
[Synonyms]

Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-
[Molecular Formula]

C24H25N3O6S
[MDL Number]

MFCD04508832
[MOL File]

781628-99-7.mol
[Molecular Weight]

483.54
Chemical PropertiesBack Directory
[density ]

1.331±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 65 mg/mL (134.43 mM)
[form ]

Solid
[pka]

7.14±0.50(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

SBI-477 is a chemical probe stimulated insulin signaling by deactivating the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain–containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes[1].
[References]

[1] Ahn B, et al. MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling. J Clin Invest. 2016 Sep 1;126(9):3567-79. DOI:10.1172/JCI87382
Spectrum DetailBack Directory
[Spectrum Detail]

Benzamide, 3-methoxy-N-[4-(4-methoxyphenyl)-2-thiazolyl]-4-[2-(4-morpholinyl)-2-oxoethoxy]-(781628-99-7)1HNMR
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