| Identification | Back Directory | [Name]
Isoniazid-D4 | [CAS]
774596-24-6 | [Synonyms]
ArMa
FSR-3-d
FSR-3-d3
ArMazid-d4
RP-5015-d4
Tubazid-d4
5015 R.P.-d4
Isoniazid-D4
Isonicotinylhydrazine-d4
Isonicotinic Acid-d4 Hydrazide
4-(Pyridyl-d4)carbonylhydrazide
4-(Hydrazinocarbonyl)pyridine-d4
4-(Pyridine-d4)carbonylhydrazine
4-(Pyridine-d4)carboxylic Hydrazide
4-(Pyridine-d4)carboxylic Acid Hydrazide
4-Pyridine-2,3,5,6-d4-carboxylic Acid Hydrazide
(4-Pyridine-2,3,5,6-D-carboxylic Acid Hydrazide | [Molecular Formula]
C6H3D4N3O | [MOL File]
774596-24-6.mol |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E | [Uses]
Labelled Isoniazid. Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic). |
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