| Identification | Back Directory | [Name]
N2-Ethylguanosine | [CAS]
77312-39-1 | [Synonyms]
N2-Ethylguanosine
Guanosine, N-ethyl- | [Molecular Formula]
C12H17N5O5 | [MDL Number]
MFCD30596290 | [MOL File]
77312-39-1.mol | [Molecular Weight]
311.29 |
| Hazard Information | Back Directory | [Uses]
N2-Ethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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