Identification | Back Directory | [Name]
MONOETHYLGLYCINEXYLIDIDE | [CAS]
7728-40-7 | [Synonyms]
L-86 MEGX MGEX Norlidocaine Lidocaine-006 Ethylglycylxylidide Lidocaine Impurity 9 N-Ethylglycinexylidide Monoethylglycylxylidide Monoethylglycinexylidine MONOETHYLGLYCINEXYLIDIDE Monoethylglycinexylidide HCl N-(N-Ethylglycyl)-2,6-xylidine Monoethyl Glycinexylidide-d6 HCl 2-(EthylaMino)-2',6'-acetoxylidide Nor Lidocaine (1.0 mg/mL in Methanol) ω-EthylaMino-2',6'-diMethyl-
acetanilide Monoethylglycinexylidide HCl (IMpurity D) Monoethylglycinexylidine HCl (IMpurity D) N-(2,6-DIMETHYLPHENYL)-2-(ETHYLAMINO)ACETAMIDE N1-(2,6-DiMethylphenyl)-2-(ethylaMino)acetaMide Acetamide, N-(2,6-dimethylphenyl)-2-(ethylamino)- Lidocaine impurity 5/Lidocaine EP Impurity D/Nor Lidocaine/N-Desethyl Lidocaine/N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide | [Molecular Formula]
C12H18N2O | [MDL Number]
MFCD00098991 | [MOL File]
7728-40-7.mol | [Molecular Weight]
206.28 |
Chemical Properties | Back Directory | [Melting point ]
242-245°C | [Boiling point ]
335.6±30.0℃ (760 Torr) | [density ]
1.047±0.06 g/cm3 (20 ºC 760 Torr) | [Fp ]
127.8±24.7℃ | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble10mg/mL, clear | [form ]
powder | [pka]
pKa 8.04(H2O,t =25±0.2,I=0.01(NaCl)) (Uncertain) | [color ]
white to beige |
Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A metabolite of Lidocaine (L397800). | [Uses]
MEGX has been used in an approach to improve the yield of N-dealkylated lidocaine. | [Definition]
ChEBI: Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function. | [Biochem/physiol Actions]
Monoethylglycinexylidide (MEGX) is an active metabolite of lidocaine. |
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