| Identification | Back Directory | [Name]
DihydrocurcuMin | [CAS]
76474-56-1 | [Synonyms]
Letestuianin B
(4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-4,6-dien-3-one
4,6-Heptadien-3-one, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-, (4Z,6E)- | [Molecular Formula]
C21H22O6 | [MDL Number]
MFCD22124989 | [MOL File]
76474-56-1.mol | [Molecular Weight]
370.4 |
| Chemical Properties | Back Directory | [Melting point ]
179-180℃ | [Boiling point ]
616.3±55.0 °C(Predicted) | [density ]
1.277±0.06 g/cm3 (20 ºC 760 Torr) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
8.35±0.60(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Orange-yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from turmeric. | [Uses]
Dihydrocurcumin has antibacterial, anti-inflammatory, anti-tumor, antioxidant, and hypolipidemic effects. | [Biological Activity]
Dihydrocurcumin, the major metabolite of curcumin, reduces lipid accumulation and oxidative stress. It can regulate the mRNA and protein levels of SREBP-1C, PNPLA3 and PPARα, increase the protein expression levels of pAKT and PI3K, and reduce the content of intracellular NO and ROS through the Nrf2 signaling pathway. |
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