| Identification | Back Directory | [Name]
N-BUTANOYL-D-ERYTHRO-SPHINGOSINE | [CAS]
74713-58-9 | [Synonyms]
CERAMIDE C4
C4 Ceramide (d18:1/4:0)
N-Butyryl-D-sphingosine
N-BUTANOYL-D-ERYTHRO-SPHINGOSINE
N-Butanoyl-D-erythro-sphingosineCeramide C4
N-Butanoyl-D-erythro-sphingosine, synthetical
(2S,3R,4E)-2-(Butyrylamino)-4-octadecene-1,3-diol
N-BUTANOYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL
N-Butanoyl-D-erythro-sphingosine, synthetical, 99+%
n-butanoyl-d-erythro-sphingosine-sphingosinesynthetical
N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]butanaMide | [Molecular Formula]
C22H43NO3 | [MDL Number]
MFCD02181206 | [MOL File]
74713-58-9.mol | [Molecular Weight]
369.58 |
| Chemical Properties | Back Directory | [Appearance]
Off-white solid | [Melting point ]
64-67°C | [Boiling point ]
499.67°C (rough estimate) | [density ]
1.0181 (rough estimate) | [refractive index ]
1.5614 (estimate) | [storage temp. ]
-20°C
| [solubility ]
DMF: 20 mg/mL; DMSO: 20 mg/mL; Ethanol: 30 mg/mL; PBS (pH 7.2): < 50 μg/ml | [form ]
A crystalline solid | [pka]
13.54±0.20(Predicted) | [CAS DataBase Reference]
74713-58-9 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white solid | [Uses]
A ceramide derivative for pharmaceutical use as antitumor agents. | [Biological Activity]
C4 Ceramide (d18:1/4:0) is implicated in a series of mutual autophosphorylation and phosphorylation actions between 3-phosphoinositide-dependent kinase 1 (PDK1) and serum/glucocorticoid-induced protein kinase 1 (SGK1). It stimulates cyclic adenosine monophosphate (cAMP)-activated chloride secretion and represses hypersecretion of interleukin-8 (IL-8). C4 Ceramide might be a potential therapeutic for cystic fibrosis (CF). | [storage]
Store at -20°C |
|
| Company Name: |
Alfa Chemistry
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1-516-6625404 |
| Website: |
https://www.alfa-chemistry.com |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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