| Identification | Back Directory | [Name]
(ISOCYANOIMINO)TRIPHENYLPHOSPHORANE | [CAS]
73789-56-7 | [Synonyms]
Nsc371099
(N-Isocyanoi
N-isocyaniminotriphenylphosphorane
(ISOCYANOIMINO)TRIPHENYLPHOSPHORANE
(N-Isocyanoimino)Triphenylphosphorane
(Isocyanoimino)triphenylphosphorane>
(N-Isocyanoimino)triphenylphosphorane 95%
1-methylidyne-2-(triphenyl-lambda~5~-phosphanylidene)diazanium
1-methylidyne-2-(triphenyl-lambda~5~-phosphanylidene)diazani... | [Molecular Formula]
C19H15N2P | [MDL Number]
MFCD09038528 | [MOL File]
73789-56-7.mol | [Molecular Weight]
302.31 |
| Chemical Properties | Back Directory | [Melting point ]
160-161 °C | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [form ]
solid | [color ]
White to Light yellow to Light orange |
| Hazard Information | Back Directory | [Uses]
Despite growing interest for therapeutic and other biological applications, cyclic peptidomimetics are challenging to synthesize. As reported by the lab of Andrei Yudin, (N-isocyanoimino)triphenylphosphorane (Pinc
) enables zwitterionic-controlled generation of peptide macrocyles from linear peptides and aldehydes. Containing a 1,3,4-oxadiazole, the resulting peptide exhibits both improved membrane permeability, lipophilicity, and aqueous solubility.
Different functional groups can be introduced by varying the aldehyde, and initial work used propionaldehyde (538124), phenylacetaldehyde (107395), and isovaleraldehyde (146455).
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| Company Name: |
Energy Chemical
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021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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