Identification | Back Directory | [Name]
EPA | [CAS]
73167-03-0 | [Synonyms]
EPA ICOSAPENT C20:5 OMEGA-3 TIMNODONIC ACID Icosapent sodium EICOSAPENTAENOIC CID EICOSAPENTAENOIC ACID EPA 5C,8C,11C,14C,17C ALL CIS 5-8-11-14-17 EPA Eicosapentaenoic Acid (sodium) C20:5 (ALL CIS-5,8,11,14,17) ACID 5,8,11,14,17-EICOSAPENTAENOIC ACID Eicosapentaenoic Acid (sodium salt) CIS-5,8,11,14,17-EICOSAPENTANEOIC ACID CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID 5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID EICOSA-5Z,8Z,11Z,14Z,17Z-PENTAENOIC ACID ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID 5,8,11,14,17-eicosapentaenoic acid, sodium salt cis-5,8,11,14,17-eicosapentaenoic acid*sodium app CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID SODIUM SALT CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID*S ODIUM APPRO (all-Z)-5,8,11,14,17-Eicosapentaenoic acid sodium salt sodium:(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic acid sodium salt tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity 5,8,11,14,17-Eicosapentaenoicacid, sodium salt (1:1), (5Z,8Z,11Z,14Z,17Z)- | [Molecular Formula]
C20H29O2.Na | [MDL Number]
MFCD00065716 | [MOL File]
73167-03-0.mol | [Molecular Weight]
324.44 |
Chemical Properties | Back Directory | [Melting point ]
−54-−53 °C(lit.) | [density ]
0.943 g/mL at 25 °C(lit.) | [refractive index ]
n20/D 1.4977(lit.) | [storage temp. ]
-20°C | [form ]
waxy solid | [color ]
white |
Hazard Information | Back Directory | [Uses]
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:
- to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
- to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
- to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice
| [Uses]
reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis. | [General Description]
Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil. | [Biochem/physiol Actions]
Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis. |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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