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ChemicalBook--->CAS DataBase List--->727721-37-1

727721-37-1

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Chemical Properties

Hazard Information

727721-37-1 Structure

727721-37-1 Structure

Identification	Back Directory
[Name] PT-ttpy
[CAS] 727721-37-1
[Synonyms] PT-ttpy
[Molecular Formula] C22H17Cl2N3Pt
[MDL Number] MFCD32264619
[MOL File] 727721-37-1.mol
[Molecular Weight] 589.38

Chemical Properties	Back Directory
[storage temp. ] 2-8°C
[solubility ] DMSO: 0.2mg/mL (warmed)
[form ] powder
[color ] faint yellow to dark orange

Hazard Information	Back Directory
[Biological Activity] Pt-ttpya metallo-organic complexis a G-quadruplex ligand th at potently induces significant telomere-associated DNA damage in cancer cells. It inhibits telomerase and/or telomere functions. Pt-ttpy induces number of chromatin defects in mitosis including chromatin bridgesultrafine bridges (UFBs)and double-stranded breaks (DSBs).

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