| Identification | Back Directory | [Name]
ZLN-024 | [CAS]
723249-01-2 | [Synonyms]
ZLN024
ZLN-024
2-[[2-(2-Bromo-4-methylphenoxy)ethyl]thio]-pyrimidine
2-[2-(2-bromo-4-methylphenoxy)ethylsulfanyl]pyrimidine
Pyrimidine, 2-[[2-(2-bromo-4-methylphenoxy)ethyl]thio]- | [Molecular Formula]
C13H13BrN2OS | [MDL Number]
MFCD05155678 | [MOL File]
723249-01-2.mol | [Molecular Weight]
325.22 |
| Chemical Properties | Back Directory | [Boiling point ]
443.3±35.0 °C(Predicted) | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [pka]
0.12±0.33(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
ZLN024 is a useful chemical reagent. | [Biological Activity]
ZLN024 is an allosteric activator of AMPK hetero-trimers. The compound ZLN024 protects against dephosphorylation of Thr172which is critical for activityand antagonizes AMPK autoinhibition. ZLM024 improves glucose tolerance and lowers total cholesterol levels in db/db mice. |
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